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. 2018 Dec 10;115(52):E12417–E12426. doi: 10.1073/pnas.1812518115

Fig. 5.

Fig. 5.

REST expression is regulated by miR-9 following axon injury in sensory neuron. (A) Differential expression of validated miR-9 targets in our previously published array (16). (B) Enriched GO molecular functions from analyzing miR-9-5p predicted and validated targets. (C) Expression level of UHRF1 and REST mRNA was analyzed by RT-qPCR in neurons expressing control or miR-9-5p/3p (n = 4 biological replicates; **P < 0.01 by t test; mean ± SEM). (D) Heatmap of REST target genes in DRG neurons at E12.5 and E17.5 and DRG neurons of naïve and 5 d after SNI. (E) Enriched GO processes for a and b cluster in D is shown.