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. 2018 Dec 29;6:35. doi: 10.1186/s41038-018-0138-8

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Retro-Diels-Alder reaction based hydrogels formation and their dissolution. a Michael addition and Diels-Alder (DA) reaction. Figure is adapted with permission from the original articles of Koehler et al. [51] (Copyright 2013 by American Chemical Society). b Formation and degradation of poly(ethylene glycaol)-oxanorbornadiene (PEG-OND) hydrogels. Figure is adapted with permission from the original articles of Higginson et al. [53] (Copyright 2015 by American Chemical Society). c The DA reaction was investigated as a cross-linking mechanism for PEG-based hydrogels. Figure is adapted with permission from the original articles of Kirchhof et al. [54] (Copyright 2013 by Royal Society of Chemistry)