Table 1.
The clinical-pathological features of the three groups of patients
| Variable | Groups (n = 89) | ||||
|---|---|---|---|---|---|
| Category | CM/ESCC (n = 23) | ESCC (n = 38) | CM (n = 28) | p-value | |
| Gender | Female | 4 (17.4%) | 7 (18.4%) | 4 (14.3%) | 0.937** |
| Male | 19 (82.6%) | 31 (81.6%) | 24 (85.7%) | ||
| Age (years) | Mean (SD) | 59 (11) | 57 (9) | 59 (11) | 0.039 *** |
| Min - Max | 37–76 | 36–75 | 37–76 | ||
| Alcohol consumption | No | 7 (31.8%) | 8 (21.1%) | 20 (71.4%) | < 0.001 * |
| Yes | 15 (68.2%) | 30 (78.9%) | 8 (28.6%) | ||
| Missing | 11 | 0 | 0 | ||
| Tobacco consumption | No | 4 (18.2%) | 6 (15.8%) | 16 (57.1%) | < 0.001 * |
| Yes | 18 (81.8%) | 32 (84.2%) | 12 (42.9%) | ||
| Missing | 1 | 0 | 0 | ||
| Tumor differentiation | Well differentiated | 5 (22.7%) | 7 (19.4%) | NA | 0.639** |
| Moderate differentiated | 16 (72.7%) | 24 (66.7%) | NA | ||
| Poorly differentiated | 1 (4.5%) | 5 (13.9%) | NA | ||
| Missing | 1 | 2 | NA | ||
| TNM Staging | I/II | 4 (23.5%) | 16 (42.1%) | NA | 0.235* |
| III/IV | 13 (76.5%) | 22 (57.9%) | NA | ||
| Missing | 6 | 0 | NA | ||
| Megaesophagus grades | GI/GII | 10 (45.5%) | NA | 4 (14.3%) | 0.025 * |
| GIII/GIV | 12 (54.5%) | NA | 24 (85.7%) | ||
| Missing | 1 | NA | 0 | ||
*Chi-square association test; **Fisher’s exact test; ***Analysis of variance. CM/ESCC – chagasic megaesophagus associated with esophageal squamous cell carcinoma; ESCC – esophageal squamous cell carcinoma without chagasic megaesophagus; CM – chagasic megaesophagus without esophageal squamous cell carcinoma; SD - standard deviation; NA – not applicable; Bold numbers - statistical significance