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. 2018 Dec 29;19:262. doi: 10.1186/s12931-018-0948-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — SMAD3 knockdown decreased SMAD3 and PAX6 expression levels. a SMAD3 and PAX6 mRNA expression levels in A549 cells transfected with siRNA and normalized to GAPDH (left panel) and GUSB (right panel). b SMAD3 and PAX6 protein expression levels in A549 cells transfected with siRNA (n = 3). c SMAD3 and PAX6 mRNA expression levels in HCC827 cells transfected with siRNA normalized to GAPDH (left panel) and GUSB (right panel). d SMAD3 and PAX6 protein expression levels in HCC827 cells transfected with siRNA. Data represent the mean ± SD. *P < 0.05 and **P < 0.01 compared with the control group