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. 2018 Dec 29;19:262. doi: 10.1186/s12931-018-0948-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — SMAD3 downregulation decreased the colony forming capacity and cell viability of A549 and HCC827 cells. a The colony forming capacity of A549 cells was detected by colony forming assay. b The cell viability of A549 cells was determined by CCK-8 assay. c The colony forming capacity of HCC827 cells was detected by colony forming assay. d The cell viability of HCC827 cells was determined by CCK-8 assay. All experiments were performed in triplicate. Data represent the mean ± SD. *P < 0.05 and **P < 0.01 compared with the NC group. ^#P < 0.05 compared with the si-SMAD3 group