Fig. 3.

Schematic illustration of the Nitrospira syntenic genomic regions containing genes for N uptake and assimilation. Inferred protein functions are indicated by color, genes are drawn to scale. The scale bar corresponds to 5 kb sequence length. Affiliation with the main Nitrospira lineages or the comammox clades (both part of Nitrospira lineage II) is given on the left-hand side. AmtB, AmtB-type ammonium transporter; CynS, cyanase; OCC, octaheme cytochrome c; NirA, ferredoxin-dependent nitrite reductase; GlnA, glutamine synthetase; GlnB, nitrogen regulatory protein PII; GlnD, protein PII uridylyltransferase; NadE, glutamine-dependent NAD(+) synthase; NirC, nitrite transporter; UreABC, urease; UrtABCDE, urea ABC-type transporter; UreEFGD, urease accessory proteins