Table 3.

Correlations between parameters measured within tissue sections incubated in the absence of DL-homocysteine (DL-Hcy) (control) and the same parameters measured within thin and thick intraluminal thrombus (ILT) and adjacent walls of abdominal aortic aneurysm (AAA) sections after incubation with different concentrations of DL-Hcy.

		AAA wall parts adjacent to ILT				Intraluminal thrombus
		Site A		Site B		Site A1		Site B1
Parameter	Correlation	r	p	r	p	r	p	r	p
MMP-2	control vs 100 μ mol/L Hcy	$\underset{\_}{0.697}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.358}$	$\underset{\_}{0.030}$	$\underset{\_}{0.843}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.742}$	$\underset{\_}{0.0001}$
	control vs 500 μ mol/L Hcy	$\underset{\_}{0.468}$	$\underset{\_}{0.003}$	$\underset{\_}{0.493}$	$\underset{\_}{0.002}$	$\underset{\_}{0.662}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.745}$	$\underset{\_}{0.0001}$
MMP-9	control vs 100 μ mol/L Hcy	$\underset{\_}{0.432}$	$\underset{\_}{0.008}$	0.208	0.217	$\underset{\_}{0.568}$	$\underset{\_}{0.0001}$	−0.062	0.717
	control vs 500 μ mol/L Hcy	$\underset{\_}{0.689}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.587}$	$\underset{\_}{0.0001}$	0.238	0.156	−0.041	0.650
TF	control vs 100 μ mol/L Hcy	$\underset{\_}{0.574}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.594}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.904}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.740}$	$\underset{\_}{0.0001}$
	control vs 500 μ mol/L Hcy	$\underset{\_}{0.634}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.402}$	$\underset{\_}{0.014}$	$\underset{\_}{0.749}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.926}$	$\underset{\_}{0.0001}$
t-PA	control vs 100 μ mol/L Hcy	$\underset{\_}{0.783}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.559}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.763}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.396}$	$\underset{\_}{0.015}$
	control vs 500 μ mol/L Hcy	0.303	0.073	$\underset{\_}{0.519}$	$\underset{\_}{0.001}$	$\underset{\_}{0.501}$	$\underset{\_}{0.002}$	0.168	0.321
Plasminogen	control vs 100 μ mol/L Hcy	0.114	0.503	$\underset{\_}{0.508}$	$\underset{\_}{0.001}$	0.311	0.065	$\underset{\_}{0.815}$	$\underset{\_}{0.0001}$
	control vs 500 μ mol/L Hcy	−0.082	0.628	$\underset{\_}{0.731}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.347}$	$\underset{\_}{0.036}$	$\underset{\_}{0.564}$	$\underset{\_}{0.0001}$
PAI-1	control vs 100 μ mol/L Hcy	$\underset{\_}{0.525}$	$\underset{\_}{0.001}$	$\underset{\_}{0.582}$	$\underset{\_}{0.0001}$	$\underset{\_}{0.379}$	$\underset{\_}{0.021}$	$\underset{\_}{0.734}$	$\underset{\_}{0.0001}$
	control vs 500 μ mol/L Hcy	$\underset{\_}{0.389}$	$\underset{\_}{0.017}$	$\underset{\_}{0.446}$	$\underset{\_}{0.006}$	$\underset{\_}{0.369}$	$\underset{\_}{0.025}$	$\underset{\_}{0.779}$	$\underset{\_}{0.0001}$

r, p, Pearson's correlation coefficient and p-value; MMP-2,9, matrix metalloproteinase 2 or 9; TF, tissue factor; t-PA, tissue plasminogen activator; and PAI-1, plasminogen activator inhibitor-1. Site A = wall adjacent to thick ILT; site B = wall adjacent to thin ILT; site A1 = thick ILT; site B1 = thin ILT. Measurement units are given in Figure 1. Underlined values show significant correlations.