Table 8.
Summary of assessments of intraocular pressure in study eyes (pooled safety population)
| KPI-121 1% BID (n=386) | Vehicle BID (n=325) | |
|---|---|---|
|
| ||
| Intraocular pressure (mmHg), n (%) | ||
| >5 mmHg increase from baseline | 19 (4.9) | 8 (2.5)a |
| >5 mmHg increase from baseline + ≥21 mmHg measurement | 5 (1.3) | 3 (0.6)a |
| ≥10 mmHg increase from baseline | 3 (0.8) | 0a |
| ≥10 mmHg increase from baseline + ≥21 mmHg measurement | 2 (0.5) | 0a |
Notes:
a
n=320; five subjects in the pooled vehicle group did not have any post-baseline IOP measurement.
Abbreviation: BID, twice daily.