Table 1.
Latin name | Inhibitor | IE | Drug tests | Plant tests | ThT interaction | Type of Aβ | Application |
Withania somnifera | yes | 49% (±8) | LS | LS | no | Aβ40, MAβ40 | Stress reduction, migraine, headache, neuralgia, swelling tumors, epilepsy, lack of memory [8–10, 58] |
Bacopa monnieri (Linn.) | yes | 74% (±13) | LS | LS | no | MAβ40 | Epilepsy, manic psychosis, depression, promoting memory [8, 9] |
Centella asiatica | yes | 78% (±5) | LS | LS | no | MAβ40 | Chronic rheumatism, increase memory, epilepsy, hysteria [8, 9] |
Nardostachys grandiflora DC. | no | 9% (±11) | LS | na | no | Aβ40, MAβ40 | Hypertension, epilepsy, hysteria, hepatitis, migraine, depression, headache, amnesia [8, 9] |
Celastrus paniculatus | no | –55% (±120) | LS | na | no | Aβ40, MAβ40 | Intellect promoting, sharpening/increase memory, diabetes mellitus [8, 9] |
Convolvulus pluricaulis | nd | 48% (±7) | LS | na | no | Aβ40 | Epilepsy, uterine disorders, anxiety, hypertension, chronic headache [8, 9] |
Commiphora wightii | no | 10% (±9) | LS | na | no | Aβ40, MAβ40 | Anxiety, epilepsy, chronic headache, uterine disorders, hypertension [8, 9] |
Curcuma longa | nd | nd | LS | na | Yes | MAβ40 | Bronchitis, allergies, high blood pressure, high Cholesterol, skin diseases [8, 9, 54] |
na, not available; LS, luminescence spectrometer; nd, not distinguishable; IE, inhibition efficiency.