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. Author manuscript; available in PMC: 2018 Dec 30.
Published in final edited form as: Pigment Cell Melanoma Res. 2011 Apr;24(2):393–394. doi: 10.1111/j.1755-148X.2011.00832.x

Figure 1.

Figure 1.

(A) Making of iDct- green fluorescent protein (GFP) mice. Dct-rtTA transgenic mice were crossed with the TRE-H2BGFP mice to get the iDct-GFP bi-transgenic mice, which show tightly regulated doxycycline-inducible GFP expression. (B) An E11.5 iDct-GFP embryo. (C) A Dct-LacZ embryo (courtesy, Dr. Ian Jackson). (D) GFP expression in the skin of a 7 days old pup is detectable in the bulb and bulge regions of the hair follicles. Blue, DAPI. (E) Skin section from an adult mouse, showing GFP+ cells in the hair follicles (demarcated in red). (F) Induction of GFP expression by a single intraperitoneal injection of doxycycline. Images have been modified from Zaidi et al.