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. Author manuscript; available in PMC: 2020 Mar 1.
Published in final edited form as: J Allergy Clin Immunol. 2018 Jun 30;143(3):844–851. doi: 10.1016/j.jaci.2018.05.021

Table 2:

HIV-specific antibodies, including both broadly neutralizing (bNAbs) and non-neutralizing antibodies (non-NAbs), in clinical trials.

HIV antibody Target Function
VRC01,
3BNC117
CD4-binding site (CD4bs)97-99 bNAbs
10-1037,
PGT135
variable region 3 (V3) glycan or high-mannose patch100,101 bNAbs
A32 CD4-inducible constant regions 1 and 2 Non-NAbs
7B2 gp41 cluster 1 Non-NAbs