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. 2018 Oct 18;293(52):20041–20050. doi: 10.1074/jbc.RA118.001858

Figure 3.

Figure 3.

Intracerebroventricular administration of the miR-27a-3p mimic reduces brain edema and maintains BBB permeability following ICH. A, the levels of miR-27a-3p in rat serum, perihematomal tissue, and the hematomal region were measured by real-time PCR 24 h after ICH (n = 6/group). B, brain water content was measured 24 h after ICH induction and miRNA treatment (n = 6/group). C, Evans blue extravasation assay was performed to assess BBB permeability following ICH (n = 6/group). *p < 0.05; **p < 0.01.