Figure 7.

Antagonizing miR-27a-3p increases BMEC monolayer permeability and blocks BMEC proliferation and migration. A, the fluorescence intensity of FITC–dextran 20 that passed through a BMEC monolayer over 120 min was measured. B, an MTT assay was performed to assess the proliferation of BMECs that were transfected with miR-NC or the miR-27a-3p inhibitor. C, a scratch wound assay was conducted to evaluate the motility of BMECs. The experiments were repeated three times. *, p < 0.05; **, p < 0.01 versus miR-NC-transfected cells.