Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 28;14:1744806918808150. doi: 10.1177/1744806918808150

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 7. — CD11b suppresses CCI-induced mechanical and thermal allodynia. Mechanical (a) and thermal (b) allodynia was measured at indicated time. (c) Q-PCR analysis of IL-6, TNF-α, and IL-10 in spinal cord of WT or CD11b-deficient mice three days after CCI. (d) Immunofluorescence staining of phorspho-p65 and phorspho-p-ERK (as indicated by white arrows) in the WT or CD11b-deficient mice three days after CCI. Scale, 20 μm. (E) Schematic diagram of CD11b-activated Src-Syk signaling keeps homeostasis of neuroinflammation. Data are presented as mean ± SEM, n = 8 (n indicates the number of animals per group); *P < 0.01. WT: wild type; TLR: toll-like receptor; IL: interleukin; TNF-α: tumor necrosis factor alpha; TGF-β: transforming growth factor beta; CCI: chronic constrictive injury; Q-PCR: quantitative PCR.