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. 2018 Nov 29;8(4):697–704. doi: 10.15171/apb.2018.078

Table 2. Results of histopathological evaluation of rat’s lung tissues, radiation group was compared to control group while radiation plus metformin group was compared to radiation group (a: significant compared to control group, ANOVA, Tukey's HSD, p<0.05).

Control Metformin treated Radiation Radiation+Metformin
Macrophage infiltration 1.00±00 1.00±00 3.66±0.57a 1.5±0.57b
Lymphocyte infiltration 1.75±0.50 1.00±00 4.00±00a 1.5±0.57b
Neutrophil infiltration 1.25±50 1.00±00 1.00±00 1.25±50
Alveolar thickness 1.00±00 1.00±00 2.66±0.57a 1.25±50b
Vascular thickness 1.00±00 1.00±00 2.00±00a 1.00±00b
Edema and thrombosis 1.00±00 1.00±00 2.00±00a 1.00±00b