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Hippocampal neuronal loss and multiple microinfarctions. (a) Wild-type sham, (b) wild-type BCAS, (c) ApoE−/− sham, and (d) ApoE−/− BCAS mice. Hippocampal neuronal loss (arrowheads) and ischemic stroke (arrow) was seen only in ApoE−/− BCAS mice (three of four ApoE−/− BCAS mice). Scale bars, 200 µm.
