Table 3.
Involvement of HAT in stem cells.
| HAT | Target | Effect in normal stem cells | Ref |
|---|---|---|---|
| CBP | Maintenance of self-renewal hematopoietic stem cells | [61] | |
|
| |||
| p300 | OCT4, SOX2, KLF4 | Stem cell reprogramming | [54] |
| Proliferation and odontogenic differentiation of human dental pulp cells | [56] | ||
| Self-renewal and pluripotency maintenance in ESCs | [57] | ||
| Proper hematopoietic differentiation | [61] | ||
|
| |||
| GCN5 | Myc | Early reprogramming initiation in mouse PSC | [62] |
| NF-κB | Osteogenic commitment of mesenchymal stem cells | [64] | |
| DKK1 | Osteogenic differentiation of periodontal ligament stem cells | [65] | |
|
| |||
| pCAF | BMPs | Osteogenic differentiation of mesenchymal stem cells | [66] |
|
| |||
| MOF | NANOG, OCT4, SOX2 | Maintenance of ESC self-renewal and pluripotency | [68] |
| Stem cell reprogramming | [69] | ||
|
| |||
| Tip60 | ESC differentiation into mesoderm and endoderm lineages | [71] | |
|
| |||
| MOZ | p16(INK4a) | Maintenance of proliferation in hematopoietic and neural stem cells | [72] |