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. Author manuscript; available in PMC: 2020 Jan 2.
Published in final edited form as: Circulation. 2019 Jan 2;139(1):24–36. doi: 10.1161/CIRCULATIONAHA.118.035640

Table 3.

Comparison of the projected number of CVD events prevented in the next ten years by achieving and maintaining 2017 ACC/AHA and JNC8PM guideline-recommended SBP Goals compared to current SBP levels, overall and within subgroups.

2017 ACC/AHA JNC7 JNC8PM Panel Member Report
Total CVD events prevented (millions, UR) CVD events prevented per 1,000 treated (UR) Total CVD events prevented (millions, UR) CVD events prevented per 1,000 treated (UR) Total CVD events prevented (millions, UR) CVD events prevented per 1,000 treated (UR)
Overall 3.0
(1.1–5.1)		 71.9
(27.0–122.3)		 2.6
(0.9–4.4)		 77.3
(28.2–134.1)		 1.6
(0.5–2.9)		 73.9
(18.0–140.5)
Sex
 Females 1.5
(0.7–2.4)		 74.8
(35.0–117.6)		 1.3
(0.1–0.3)		 83.7
(37.2–133.0)		 0.8
(0.2–1.4)		 52.0
(8.2–113.7)
 Males 1.5
(0.7–2.3)		 80.1
(37.7–124.0)		 1.3
(0.6–2.0)		 86.7
(39.8–137.0)		 0.8
(0.3–1.3)		 70.9
(17.5–134.6)
Race
 White 2.1
(1.0–3.2)		 76.8
(37.4–115.5)		 1.8
(0.2–0.4)		 85.9
(39.9–132.2)		 1.0
(0.4–1.8)		 81.6
(28.5–138.7)
 Black 0.4
(0.2–0.7)		 75.2
(33.6–131.1)		 0.4
(0.2–0.7)		 81.0
(36.5–140.4)		 0.3
(0.1–0.5)		 82.7
(27.6–161.1)
 Hispanic 0.3
(0.1–0.4)		 82.3
(38.7–124.0)		 0.3
(0.1–0.4)		 86.7
(38.6–134.1)		 0.2
(0.1–0.3)		 82.4
(29.8–139.1)
Age, years
 <65 1.0
(0.4–1.6)		 51.4
(19.9–85.6)		 0.8
(0.3–1.4)		 55.9
(20.3–95.5)		 0.5
(0.2–0.9)		 51.3
(17.3–94.4)
 ≥65 2.0
(1.0–3.0)		 99.7
(48.3–150.7)		 1.8
(0.8–2.8)		 108.5
(51.1–167.0)		 1.1
(0.4–1.8)		 116.4
(40.8–197.1)
 ≥ 65 and robust† 1.5
(0.8–2.3)		 104.1
(56.0–157.5)		 1.4
(0.7–2.1)		 109.0
(55.1–167.3)		 0.7
(0.1–1.4)		 73.4
(8.0–153)
High-risk groups
 Chronic kidney disease 1.7
(0.9–2.5)		 126.6
(68.9–183.2)		 1.7
(0.9–2.5)		 126.6
(68.9–183.2)		 1.0
(0.5–1.6)		 121.0
(53.3–188.6)
 Diabetes 1.1
(0.4–1.7)		 80.8
(34.3–129.4)		 1.1
(0.4–1.7)		 80.8
(34.3–129.4)		 0.5
(0.2–0.9)		 102.8
(39.1–174.9)
 Clinical CVD 0.9
(0.4–1.4)		 126.5
(60.0–192.5)		 0.8
(0.4–1.3)		 139.2
(66.1–210.4)		 0.5
(0.2–0.8)		 149.7
(61.2–240.5)

ACC: American College of Cardiology; AHA: American Heart Association; CVD: cardiovascular disease; JNC7: Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; SBP: systolic blood pressure; UR: uncertainty range.

†

Robust only is defined in NHANES by defined by walking at least 0.8 m/s in the standard 20-foot walk test, a threshold based on the prior studies recommending this cut-point and because it aligned with more comprehensive assessments of frailty and discriminated between survival times. Prior research has shown that among the traditional components used to assess frailty, slow gait speed has the strongest prognostic ability.22–25 Robust only is defined in REGARDS as without a history of falls or impaired mobility at the baseline visit.