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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Plast Reconstr Surg. 2019 Jan;143(1):77e–87e. doi: 10.1097/PRS.0000000000005091

Figure 2. Prox1+/− mice have amplified inflammatory responses following lymphatic injury.

Figure 2.

A. Schematic depiction of popliteal lymph node dissection (PLND).

B. Quantification of CD45+ cells within 50 μm of LYVE-1+ lymphatic vessels [one-way ANOVA, mean (S.D.); n=4–5/group; 4 high-powered fields (h.p.f.)/mouse, P=0.15 and P=0.017 for pre- and post-PLND, respectively].

C. Quantification of CD4+ cells [left; one-way ANOVA, mean (S.D.); n=4–5/group; 4 h.p.f./mouse, P=0.048 and P=0.0075 for pre- and post-surgery evaluation, respectively] and F4/80+ macrophages [right; one-way ANOVA, mean (S.D.); n=5/group; 4 h.p.f./mouse, P=0.019 and P=0.026 for pre- and post-PLND, respectively] within 50 μm of LYVE-1+ lymphatic vessels.