Table 4.
Salivary concentrations according to anti-hypertensive treatments.
Diuretics | Beta-blockers | Calcium blockers | ACEi or anti-AT1 | |||||
---|---|---|---|---|---|---|---|---|
No | Yes | No | Yes | No | Yes | No | Yes | |
N | 177 | 64 | 190 | 51 | 207 | 34 | 151 | 90 |
Age | 64 ± 10 | 70 ± 9∗∗∗ | 65 ± 10 | 69 ± 8∗∗∗ | 65 ± 10 | 70 ± 9∗∗ | 63 ± 10 | 70 ± 9∗∗∗ |
Women | 30% | 33% | 30% | 31% | 33% | 15%∗ | 32% | 27% |
Sodium (mM) | 14.9 (12.1–19.3) | 15.4 (12.9–19.2) | 14.8 (12.0–17.7) | 16.8 (13.7–22.0)∗∗ | 15.2 (12.3–19.45) | 14.9 (11–7-17.6) | 14.9 (12.0–19.8) | 15.3 (12.6–17.9) |
Potassium (mM) | 30.3 (25.4–36.2) | 34.2 (26.7–40.0)∗ | 30.1 (25.4–36.0) | 34.9 (29.3–42.7)∗∗ | 31.3 (25.4–36.2) | 31.2 (26.4–45.0) | 31.02 (25.3–36.4) | 31.7 (26.0–37.8) |
Calcium (mM) | 0.30 (0.24–0.39) | 0.32 (0.25–0.43) | 0.29 (0.24–0.39) | 0.35 (0.27–0.43)∗∗ | 0.30 (0.24–0.39) | 0.32 (0.26–0.49) | 0.30 (0.24–0.39) | 0.31 (0.25–0.42) |
Phosphate (mM) | 6.55 (5.22–8.92) | 7.16 (5.09–9.42) | 6.49 (5.09–8.82) | 7.26 (5.71–9.94) | 6.58 (5.13–8.77) | 6.67 (5.33–11.96)∗ | 6.46 (5.13–9.05) | 6.69 (5.25–8.80) |
Data are expressed as either mean ± SD or median (interquartile range) for normally and nonnormally distributed data, respectively. Statistically significant differences were determined using either a Student's t-test (normally distributed data) or Wilcoxon signed-rank test (nonnormally distributed data) for continuous variable. A chi-square test was used for categorical data. ∗ P < 0.05; ∗∗ P < 0.01; ∗∗ P < 0.001 vs. no treatment.