Table 3.
Sensitivity, specificity, positive predictive value, and negative predictive value for prediction of mortality determined by logistic regression
Variable | Cutoff point* | SE | SP | PPV | NPV |
---|---|---|---|---|---|
MELD score > 17 | 0.3056 | 57.89 | 78.99 | 30.56 | 92.16 |
∆MELD ≥ 1 | 0.5455 | 85.71 | 79.17 | 54.55 | 95.00 |
CTP score > 8 | 0.7700 | 93.33 | 60.61 | 26.42 | 98.36 |
∆CTP ≥ 1 | 0.5333 | 80.00 | 82.93 | 53.33 | 94.44 |
2 variables (CTP score > 8 + ∆MELD ≥ 1) | 0.9018 | 75.00 | 97.73 | 90.00 | 93.48 |
3 variables (CTP score > 8 + ∆MELD ≥ 1 + ∆CTP ≥ 1) | 0.1550 | 90.00 | 84.62 | 60.00 | 97.06 |
4 variables (CTP score > 8 + ∆MELD ≥ 1 + MELD score > 17 + ∆CTP ≥ 1) | 0.1565 | 90.00 | 84.62 | 60.00 | 97.06 |
SE – sensitivity; SP – specificity; PPV – positive predictive value; NPV – negative predictive value
Cutoff point means the classification threshold probability. The probability is used to classify patients as surviving (the probability less than this critical value) or non-surviving (the probability equal to or more than the cutoff point) in a logistic regression.