Table 3.
Association between BMI categories and the genotypes in severely obese patients.
| Genotypes | BMI (kg/m2) | p value∗ | Adjusted p valuea | |
|---|---|---|---|---|
| 35–49.9 | ≥50 | |||
| PPARG2 Pro12Ala (N=146) | 0.123 | 0.154 | ||
| ProPro (N=127) | 95 (74.8) | 32 (25.20) | ||
| Ala carriers (N=19) | 11 (57.9) | 8 (42.1) | ||
| IL6 -174G >C (N=148) | 0.907 | 0.851 | ||
| GG (N=96) | 71 (74.0) | 25 (26.0) | ||
| C carriers (N=52) | 38 (73.1) | 14 (26.9) | ||
| Genotype combination (N=145) | 0.361† | 0.257 | ||
| No variants (N=78) | 59 (75.6) | 19 (24.4) | ||
| PPARG2 variant only (N=48) | 36 (75.0) | 12 (25.0) | ||
| IL6 variant only (N=15) | 9 (60.0) | 6 (40.0) | ||
| Both variants (N=4) | 2 (50.0) | 2 (50.0) | ||
Data are presented as N (%). BMI: body mass index. ∗Chi-squared test; †Fisher's exact test; aadjusted for age, gender, sedentary time, and diabetes.