Table 4.
MicroRNAs differentially expressed in ZO-Rap versus ZO-C and their similarity to microRNAs that were differentially expressed in ZL-Rap versus ZL-C.
| MicroRNA | ZO-Rap/ZO-C | ZL-Rap/ZL-C | Nature of Association with human or animal model pathology | ||
|---|---|---|---|---|---|
| Diabetes | Cardiac fibrosis | CVD | |||
| miR-743a-5p | 2.25 | 1.09; p = N.S. | — | — | Mediates mitochondrial oxidative stress [43] |
| miR-1843-3p | −2.25 | 2 | — | — | — |
| miR-511-3p | −2.25 | −1.7 | — | — | Suppressed in moX-LDL-induced VSMC transformation in atherosclerosis [44] |
| miR-409b | −2.25 | 1.45; p = N.S. | — | — | — |
N.S.: not significant. Please see Supplemental Table 3 for the exact gene expression levels and p values.