Table 4.
Predicted disease genes on IntAct with top 10 prediction scores and at least 10 publications in PubMed records
| Disease | Rank | Gene symbol | # PMs | Related diseases in PubMed records |
|---|---|---|---|---|
| Breast Cancer (BC) | 1 | STK11 | 23 | Breast Carcinoma |
| 6 | AKT2 | 11 | Malignant neoplasm of breast | |
| 7 | PGR | 465 | Malignant neoplasm of breast, Breast Carcinoma | |
| 8 | RAD51C | 14 | Malignant neoplasm of breast, Hereditary Breast and Ovarian Cancer Syndrome | |
| Diabetes Mellitus (DM) | 1 | AKT1 | 15 | Diabetes Mellitus Non-Insulin-Dependent, Diabetes Mellitus |
| Lung Cancer (LC) | 1 | TNFSF10 | 39 | Carcinoma of lung, Non-Small Cell Lung Carcinoma |
| 3 | AURKA | 13 | Malignant neoplasm of lung | |
| 4 | IL24 | 20 | Lung Neoplasms, Carcinoma of lung |