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. 2018 Dec 27;12:257–267. doi: 10.2147/OTT.S181062

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© 2019 Guo et al. This work is published and licensed by Dove Medical Press Limited

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Cell colony formation ability was assessed by plate clone formation assay.

Notes: Combination group showed less clone formation compared with single drug in tongue squamous cancer cells. “C” represents control group, “E” represents cells were treated with EVO for 48 hours. “G” represents cells were treated with GEM for 48 hours. “EG” represents cells were sequential exposed to EVO for 24 hours followed by GEM for 24 hours. *P<0.05 and **P<0.01.

Abbreviations: EVO, evodiamine; GEM, gemcitabine.