Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Flow cytometric analysis in patient 3 shows that circulating lymphocytes are mainly CD19+B cells (81%) with high expression of surface IgM and restricted lambda phenotype (99%) (A). IgH, IgLambda, and IgKappa (VkJk and Kde) clonality profiles from the diagnostic samples suspected of Bcell clonal proliferation show a clear pattern of polyclonal rearrangements. These reproducible profiles provide evidence for a polyclonal proliferation of the monotypic IgM Lambdapositive B cells (B).
