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. 2018 Nov 30;12(11):18–24. doi: 10.3941/jrcr.v12i11.3415

Table 2.

Differential diagnoses table for Xanthogranulomatous pyelonephritis (XGP).

US CT MRI
XGP Renal enlargement with pelvicalyceal dilatation, parenchymal destruction and multiple anechoic areas with hyperechogenic septa. Multiloculated appearance (low density rounded areas throughout the enlarged left kidney): bear’s paw sign. T1-weighted:
  • Cavitary borders: Hyperintense

  • Cavitary fluid: Hypointense

  • Perirenal strands: Hypointense

T2-weighted:
  • Cavitary borders: Isointense

  • Cavitary fluid: Hyperintense

  • Perirenal strands: Hypointense

  • Fluid level: Present

Gd-DTPA:
  • Cavitary borders: Enhancement.

  • Cavitary fluid: No enhancement

  • Perirenal strands: Enhancement

Clear cell RCC Can be hypo-iso-hyperechoic and heterogeneous [10]. Hypodense and hyperdense parenchymal mass with hemorrhage and necrosis [10].
  • Hypo to isointense on T1.

  • Iso to hyperintense on T2.

  • Drop on in signal due to microscopic fat [10].

Sarcomatoid RCC Large solid to cystic mass [10,11]. Solid hypodense mass [10,11]. Necrosis is evident as hypointense signal on T1 with corresponding T2 hyperintensity [10,11].
Tuberculosis Necrotic heterogeneous mass Mass with calcifications and cortical scarring
  • Hypoperfused areas on contrast-enhanced, fat-suppressed T1

  • Central hyperintense areas on T2 [12].

Angiomyolipoma Intense echogenicity
Well-circumscribed [13].
  • Cortical heterogeneous lesion with fatty (low) attenuation

  • Variable enhancement pattern [13].

  • High intensity on non-enhanced T1 (fat)

  • Isointense to perinephric fat on T2 [13].

Renal Abscess Anechoic/hypoechoic complex cystic mass [14]. Low-attenuation mass with peripheral enhancement and possible gas collections [14]. Peripherally enhancing mass and gas collections [14].