Table 2.
Association of T- and non-T cell related inflammatory markers with anhedonia and other depressive and symptoms
| Anhedonia | Modified QIDS-SR* | |||
|---|---|---|---|---|
| F value | p value | F value | p value | |
| Interleukin 17 | ||||
| Age | 0.24 | 0.628 | 1.30 | 0.256 |
| BMI | 1.13 | 0.289 | 0.92 | 0.339 |
| Gender | 18.02 | <0.001 | 11.15 | 0.001 |
| Log of IL-17 | 4.68 | 0.032 | 1.22 | 0.271 |
| Th1-factor | ||||
| Age | 0.76 | 0.386 | 1.18 | 0.278 |
| BMI | 1.43 | 0.234 | 1.28 | 0.259 |
| Gender | 18.89 | <0.001 | 11.16 | 0.001 |
| Th1-factor | 9.72 | 0.002 | 0.31 | 0.580 |
| Th2-factor | ||||
| Age | 0.63 | 0.429 | 1.22 | 0.270 |
| BMI | 0.65 | 0.422 | 1.38 | 0.243 |
| Gender | 20.18 | <0.001 | 11.41 | <0.001 |
| Th2-factor | 10.99 | 0.001 | 0.64 | 0.422 |
| Non-T cell-factor | ||||
| Age | 0.27 | 0.603 | 0.66 | 0.419 |
| BMI | 0.73 | 0.393 | 0.48 | 0.490 |
| Gender | 16.64 | <0.001 | 7.53 | 0.007 |
| Non-Th1/Th2-factor | 7.07 | 0.009 | 5.58 | 0.019 |
*
Modified QIDS is QIDS-SR (Quick Inventory of Depressive Symptomatology Self-Rated version) minus the anhedonia item, Th1 is T-helper cell type 1, Th2 is T-helper cell type 2, Th1 cytokines include interferon gamma and tumor necrosis factor alpha (TNF-α), Th2 cytokines include interleukin (IL) 4, IL-5, IL-9, and IL-13, non-Th1/Th2 cytokines include IL-1 beta (IL-1β), IL-1 receptor antagonist, IL-8, IL-6, and macrophage inflammatory protein (MIP) 1 alpha and beta.