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. 2018 Dec 31;13(12):e0209932. doi: 10.1371/journal.pone.0209932

Table 1. Characteristics of patients with MDR-TB.

Variables Number (%)
Demographic Factors
Sex
 Male 214 (64.8)
 Female 116 (35.2)
Age
 ≤ 30 years 99 (30.0)
 31–50 years 162 (49.1)
 > 50 years 69 (20.9)
 Mean ± SD (39.45±13.28), Minimum 18, Maximum 77
BMI
 < 18.5 85 (25.8)
 ≥ 18.5 245 (74.2)
 Mean ± SD (20.96±2.79), Minimum 10.70, Maximum 26.20
Geographical Accessibility
Residence
 Rural 83 (25.2)
 Urban 247 (74.8)
Disease Factors
Type of patient
 New case 35 (10.6)
 Previously treated case 295 (89.4)
  Relapse 154 (52.2)
  Treatment after failure (Category I) 70 (23.7)
  Treatment after failure (Category II) 67 (22.7)
  Default 4 (1.2)
Contact with MDR-TB patient
 Absent 212 (64.2)
 Present 118 (35.8)
Diabetes mellitus
 Absent 301 (91.2)
 Present 29 (8.8)
HIV coinfection
 Absent 298 (90.3)
 Present 32 (9.7)
Lung cavitation
 Absent 307 (93.0)
 Present 23 (7.0)
  Unilateral 16 (69.6)
  Bilateral 7 (30.4)
Smear grade
 Negative 28 (8.5)
 1+ 142 (43.0)
 2+ 66 (20.0)
 3+ 94 (28.5)
Drug-resistance pattern
 HR 296 (89.7)
 SHR 18 (5.5)
 SHRE 16 (4.8)
Treatment duration (n = 269)
 20 months 230 (85.5)
 24 months 39 (14.5)
Culture conversion time (n = 269)
 Short (< 152 Days) 117 (43.5)
 Long (≥ 152 Days) 152 (56.5)
 Median 152, IQR 147 (94–241), Minimum 90, Maximum 365
Treatment outcome (n = 330)
 Successful 269 (81.5)
  Cured 210 (63.6)
  Completed 59 (17.9)
 Poor 61 (18.5)
  Lost to follow-up 9 (0.03)
  Failed 3 (0.01)
  Died 48 (14.5)
  Not evaluated 1 (0.00)

Abbreviations: MDR-TB, multidrug-resistant tuberculosis; SD, standard deviation; BMI, body mass index; IQR, interquartile range; S, streptomycin; H, isoniazid; R, rifampin; E, ethambutol.