Table 1. Characteristics of patients with MDR-TB.
Variables | Number (%) |
---|---|
Demographic Factors | |
Sex | |
Male | 214 (64.8) |
Female | 116 (35.2) |
Age | |
≤ 30 years | 99 (30.0) |
31–50 years | 162 (49.1) |
> 50 years | 69 (20.9) |
Mean ± SD (39.45±13.28), Minimum 18, Maximum 77 | |
BMI | |
< 18.5 | 85 (25.8) |
≥ 18.5 | 245 (74.2) |
Mean ± SD (20.96±2.79), Minimum 10.70, Maximum 26.20 | |
Geographical Accessibility | |
Residence | |
Rural | 83 (25.2) |
Urban | 247 (74.8) |
Disease Factors | |
Type of patient | |
New case | 35 (10.6) |
Previously treated case | 295 (89.4) |
Relapse | 154 (52.2) |
Treatment after failure (Category I) | 70 (23.7) |
Treatment after failure (Category II) | 67 (22.7) |
Default | 4 (1.2) |
Contact with MDR-TB patient | |
Absent | 212 (64.2) |
Present | 118 (35.8) |
Diabetes mellitus | |
Absent | 301 (91.2) |
Present | 29 (8.8) |
HIV coinfection | |
Absent | 298 (90.3) |
Present | 32 (9.7) |
Lung cavitation | |
Absent | 307 (93.0) |
Present | 23 (7.0) |
Unilateral | 16 (69.6) |
Bilateral | 7 (30.4) |
Smear grade | |
Negative | 28 (8.5) |
1+ | 142 (43.0) |
2+ | 66 (20.0) |
3+ | 94 (28.5) |
Drug-resistance pattern | |
HR | 296 (89.7) |
SHR | 18 (5.5) |
SHRE | 16 (4.8) |
Treatment duration (n = 269) | |
20 months | 230 (85.5) |
24 months | 39 (14.5) |
Culture conversion time (n = 269) | |
Short (< 152 Days) | 117 (43.5) |
Long (≥ 152 Days) | 152 (56.5) |
Median 152, IQR 147 (94–241), Minimum 90, Maximum 365 | |
Treatment outcome (n = 330) | |
Successful | 269 (81.5) |
Cured | 210 (63.6) |
Completed | 59 (17.9) |
Poor | 61 (18.5) |
Lost to follow-up | 9 (0.03) |
Failed | 3 (0.01) |
Died | 48 (14.5) |
Not evaluated | 1 (0.00) |
Abbreviations: MDR-TB, multidrug-resistant tuberculosis; SD, standard deviation; BMI, body mass index; IQR, interquartile range; S, streptomycin; H, isoniazid; R, rifampin; E, ethambutol.