Table 3. Effects of treatment delay on disease infectivity, severity, and treatment efficacy.
Treatment Delay | Lung Cavitation ᶲ n (%) |
RR (95% CI) |
Smear Grade * n (%) |
RR (95% CI) |
Resistance Pattern * n (%) |
RR (95% CI) |
Culture Conversion * n (%) |
RR (95% CI) |
||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Present | Absent | High | Low | > HR | HR | Long | Short | |||||
Long | 14 | 156 | 1.46 | 96 | 74 | 1.41 | 26 | 144 | 3.06 | 89 | 42 | 1.49 |
(8.2) | (91.8) | (0.65–3.29) | (56.5) | (43.5) | (1.12–1.78) | (15.3) | (84.7) | (1.43–6.56) | (67.9) | (32.1) | (1.19–1.85) | |
Short | 9 | 151 | 1.00 | 64 | 96 | 1.00 | 8 | 152 | 1.00 | 63 | 75 | 1.00 |
(5.6) | (94.4) | (40.0) | (60.0) | (5.0) | (95.0) | (45.7) | (54.3) | |||||
Total | 23 | 307 | 160 | 170 | 34 | 296 | 152 | 117 | ||||
(7.0) | (93.0) | (48.5) | (51.5) | (10.3) | (89.7) | (56.5) | (43.5) |
Resistance pattern was categorized as HR (resistance to isoniazid and rifampicin only) and > HR (resistance to SHR and SHRE). Treatment delay was categorized as short delay (< 105 days) and long delay (≥ 105 days). Abbreviations: CI, confidence interval; RR, risk ratio.
ᶲ p value 0.39,
* p value < 0.05 Significant