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. 2018 Dec 31;13(12):e0203340. doi: 10.1371/journal.pone.0203340

Fig 1. Research pipeline used to identify potential anti-schistosomiasis drugs.

Fig 1

a) TDR Targets Database supplied the S. mansoni energy metabolism target identity; Gene DB and Protein were used to obtain each target's peptide sequence. b) DrugBank and TTD were used to search for approved drugs. c) Promiscuous was used to identify the interactions between the drug-target protein and possible side effects of the interaction; PubMed was used to acquire articles on in vitro and/or in vivo tests with the identified drugs.