Table 1. Demographic, anthropometric and disease specific characteristics in individuals with Friedreich ataxia and control subjects.
| FRDA n = 78 |
Controls n = 54 |
p | |
|---|---|---|---|
| Male / Female | 35/43 | 25/29 | NS |
| Age (years) | 31.1±9.3 | 31.9±8.8 | NS |
| Height (cm) | 170±10 | 169±8 | NS |
| Weight (kg) | 68.5±13.5 | 67.5±11.7 | NS |
| BSA (m2) | 1.79±0.20 | 1.77±0.18 | NS |
| BMI (kg/m2) | 23.6±4.4 | 23.5±2.9 | NS |
| Heart rate (/min) | 74.6±10.8 | 62.4±10.6 | <0.001 |
| Systolic BP (mmHg) | 111±14 | 116±12 | NS |
| Diastolic BP (mmHg) | 69±10 | 68±10 | NS |
| GAA1 | 662±195 | ||
| GAA2 | 881±205 | ||
| Age at onset of symptoms (years) | 13.5±4.9 | ||
| Symptom duration (years) | 18.1±9.5 |
BMI—body mass index, BP—blood pressure, BSA—body surface area, GAA1—number of GAA repeats in the shorter allele of FXN, GAA2—number of GAA repeats in longer allele of FXN