Table 2. Left ventricular structure and function in individuals with Friedreich ataxia and control subjects.
FRDA | Controls | P | |
---|---|---|---|
LVEDD (cm) | 4.6±0.5 | 4.8±0.4 | 0.001 |
SWT (cm) | 1.1±0.2 | 0.8±0.1 | <0.001 |
PWT (cm) | 1.1±0.2 | 0.8±0.1 | <0.001 |
RWT | 0.49±0.12 | 0.34±0.05 | <0.001 |
LVEDL (cm) | 8.1±0.7 | 8.7±0.7 | <0.001 |
LV mass index (g/m2) | |||
Male | 115±34 | 87±17 | <0.001 |
Female | 88±19 | 67±16 | <0.001 |
Fractional shortening (%) | 40.3±7.4 | 36.2±5.3 | <0.001 |
Ejection fraction (%) | 65±7 | 65±6 | 0.70 |
LV—left ventricular, LVEDD, left ventricular end-diastolic diameter, LVEDL—left ventricular end-diastolic length, PWT—posterior wall thickness, RWT—relative wall thickness, SWT—septal wall thickness