Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
DCAC can induce inflammasome NLRP3/caspase1 and ROS-related ERK/AKT/mTOR activation in Kupffer cells, leading to increased apoptosis and impaired phagocytosis. Ultimately, delayed clearance of apoptotic bodies due to compromised Kupffer cell function will result in the breakdown of self-tolerance, autoimmunity, and eventually AIH. “------”, established with parent compound TCE.
