Trends in age-adjusted incidence rate of breast cancer by stage among women aged 40–74 years, 2006–2014. (A) Among women 40–49 years of age. (B) Among women 50–74 years of age.
Notes: Red arrow indicates screening guideline change in 2009 for breast cancer. Lines were joinpoint regression lines. Among women aged 40–49 years: In situ: 2006–2014 APC=0.8, 95% CI= –0.3, 1.9, p=0.12; Localized: 2006–2014 APC=0.6, 95% CI=0.1, 1.2, p=0.026; Regional: 2006–2014 APC= –0.8, 95% CI= –1.2, –0.5, p<0.001; Distant: 2006–2009 APC=5.0, 95% CI= –0.2, 10.5, p=0.055; 2009–2014 APC= –0.4, 95% CI= –2.5, 1.7, p=0.63; 2006–2009 vs 2009– 2014, p=0.055. Among women aged 50–74 years: In situ: 2006–2014 APC=0.0, 95% CI= –0.9, 0.8, p=0.93; Localized: 2006–2014 APC=1.1, 95% CI=0.7, 1.5, p<0.001; Regional: 2006–2014 APC= –1.5, 95% CI= –1.9, –1.2, p<0.001; Distant: 2006–2009 APC=2.9, 95% CI=1.4, 4.45, p=0.006; 2009–2014 APC=0.5, 95% CI= –0.1, 1.1, p=0.085; 2006–2009 vs 2009–2014, p=0.015.
J -, joinpoint regression line; APC, annual percentage changes.