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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Am J Prev Med. 2019 Jan;56(1):100–108. doi: 10.1016/j.amepre.2018.08.018

Table 1.

Age-Adjusted Incidence Rate of Breast Cancer by Stage Among Women Aged 40–74 Years, USCS 2006–2009 and 2011–2014

Incidence rate, per 100,000 (95% CI) RR (95% CI)
Variable 2006–2009 2011–2014

Among women aged 40–49 years
    All cases 202.8 (201.9, 203.7) 203.4 (202.4, 204.4) 1.00 (1.00, 1.01)
    All cases by race/ethnicity
        Hispanic 152.9 (150.6, 155.1) 150.1 (148.1, 152.2) 0.98 (0.96, 1.00)
        Non-Hispanic white 213.2 (212.1, 214.4) 215.5 (214.2, 216.7) 1.01 (1.00, 1.02)
        Non-Hispanic black 195.7 (193.2, 198.2) 201.8 (199.2, 204.4) 1.03 (1.01, 1.05)
        Asian or Pacific Islander 181.9 (178.1, 185.7) 195.1 (191.5, 198.8) 1.07 (1.04, 1.10)
    Invasive breast cancer 153.2 (152.4, 154) 153.1 (152.2, 153.9) 1.00 (0.99, 1.01)
    Invasive breast cancer by race/ethnicity
        Hispanic 118.5 (116.5, 120.4) 115.2 (113.4, 117) 0.97 (0.95, 0.99)
        Non-Hispanic white 159.4 (158.4, 160.4) 161.2 (160.2, 162.3) 1.01 (1.00, 1.02)
        Non-Hispanic black 156.8 (154.5, 159.1) 157.5 (155.3, 159.8) 1.00 (0.98, 1.03)
        Asian or Pacific Islander 131.2 (128, 134.5) 140.7 (137.6, 143.8) 1.07 (1.04, 1.11)
    Stage of breast cancer
        In situ 49.6 (49.1, 50) 50.3 (49.9, 50.8) 1.02 (1.00, 1.03)
        Localized 86 (85.4, 86.6) 88.3 (87.6, 88.9) 1.03 (1.02, 1.04)
        Regional 56.8 (56.3, 57.3) 54.4 (54, 54.9) 0.96 (0.95, 0.97)
        Distant 7.2 (7, 7.3) 7.6 (7.4, 7.8) 1.06 (1.02, 1.10)
Among women aged 50–74 years
    All cases 395.8 (394.8, 396.8) 396.8 (395.9, 397.8) 1.00 (1.00, 1.01)
    All cases by race/ethnicity
        Hispanic 297 (294, 300) 299.4 (296.8, 302) 1.01 (0.99, 1.02)
        Non-Hispanic white 411.9 (410.7, 413) 410.3 (409.2, 411.4) 1.00 (0.99, 1.00)
        Non-Hispanic black 385.9 (383, 389) 407.6 (404.8, 410.4) 1.06 (1.05, 1.07)
        Asian or Pacific Islander 281.3 (277.3, 285.4) 305.9 (302.2, 309.6) 1.09 (1.07, 1.11)
    Invasive breast cancer 312 (311.1, 312.8) 314.5 (313.6, 315.3) 1.01 (1.00, 1.01)
    Invasive breast cancer by race/ethnicity
        Hispanic 237.6 (234.9, 240.3) 237.9 (235.6, 240.3) 1.00 (0.99, 1.02)
        Non-Hispanic white 324.8 (323.7, 325.8) 326.6 (325.7, 327.6) 1.01 (1.00, 1.01)
        Non-Hispanic black 303.5 (300.9, 306.2) 316.5 (314, 319) 1.04 (1.03, 1.06)
        Asian or Pacific Islander 212.6 (209.1, 216.1) 229.8 (226.6, 233) 1.08 (1.06, 1.10)
    Stage of breast cancer
        In situ 83.8 (83.4, 84.3) 82.4 (82, 82.8) 0.98 (0.98, 0.99)
        Localized 196.5 (195.8, 197.2) 206.6 (205.9, 207.3) 1.05 (1.05, 1.06)
        Regional 91.5 (91.1, 92) 84.1 (83.7, 84.5) 0.92 (0.91, 0.93)
        Distant 16.9 (16.7, 17.2) 18.0 (17.8, 18.2) 1.06 (1.05, 1.08)

Notes: Data were from U.S. Cancer Statistics (USCS), the combined data from the Centers for Disease Control and Prevention (CDC’s) National Program for Cancer Registries (NPCR) and the National Cancer Institute’s (NCI’s) Surveillance, Epidemiology, and End Results (SEER) Program. Boldface indicates statistical significance (p<0.05). Rates are per 1,000,000 and age-adjusted to the 2000 U.S. Standard Population. CIs are 95% for rates (Tiwari method). Differences in age-adjusted 4-year average annual rates between 2011–2014 and 2006–2009 were evaluated using rate ratio (RR) and the corresponding 95% CI. Each RR was derived from a stratified model in a specified population (different age groups, races, or stages).