Figure 9. LepR^b expression in the carotid bodies (CB) of LepR^b‐deficient db/db mice increased minute ventilation at isocapnic hypoxia (10% O₂ + 3% CO₂).

A and B, V _E calculated as tidal volume per body weight (V _T) × respiratory rate (RR). RR (C and D) and V _T (E and F) before (baseline) and 15 days after Ad‐LepR^b (n = 9) or Ad‐LacZ (n = 6) infection, at the same conditions. ^* P < 0.05 and ^** P < 0.01 using the Wilcoxon test.