Table 2.
Intact carotid bodies | Carotid sinus nerve dissection | |||||||
---|---|---|---|---|---|---|---|---|
Leptin infusion (n = 12) | Saline infusion (n = 12) | Leptin (n = 9) | Saline infusion (n = 9) | |||||
Baseline | 48 h Leptin pump | Baseline | 48 h Saline pump | Baseline | 48 h Leptin pump | Baseline | 48 h Saline pump | |
Body weight (g) | 25.42 ± 0.7 | 24.13 ± 0.8*** | 25.31 ± 0.7 | 25.6 ± 07 | 25.9 ± 1.4 | 24.9 ± 1.1* | 26.5 ± 0.7 | 27.1 ± 0.6 |
Body temperature (°C) | 35.2 ± 0.1 | 36.6 ± 0.2*** | 35.5 ± 0.1 | 35.7 ± 0.1 | 35.5 ± 0.2 | 36.6 ± 0.2* | 35.6 ± 0.2 | 35.6 ± 0.2 |
Food intake (g/day) | 3 ± 0.1 | 1.35 ± 0.1** | 3.2 ± 0.1 | 3.4 ± 0.06 | 3.7 ± 0.01 | 1.5 ± 0.8*** | 3.6 ± 0.04 | 3.2 ± 0.8 |
Leptin (ng/mL) | ND | 34.9 ± 4.3 | ND | 1.2 ± 0.3††† | ND | 36.1 ± 8.3 | ND | 1.5 ± 0.6†† |
* P < 0.05, ** P < 0.01, *** P < 0.001 for differences between baseline and leptin pump; †† P < 0.01 and ††† P < 0.001 for the difference between saline and leptin infusion. ND, not done. Results are presented as mean ± SEM.