Table 3.

Basic characteristics of C57BL/6J mice during saline and leptin infusion before and after sham surgery

	Intact carotid bodies				Sham carotid sinus nerve dissection
	Leptin infusion (n = 5)		Saline infusion (n = 5)		Leptin (n = 5)		Saline infusion (n = 5)
	Baseline	48 h Leptin pump	Baseline	48 h Saline pump	Baseline	48 h Leptin pump	Baseline	48 h Saline pump
Body weight (g)	23.2 ± 0.8	21.7 ± 0.8***	22.5 ± 0.6	22.5 ± 0.6	24.6 ± 0.7	20.8 ± 0.4*	23.2 ± 0.5	23.1 ± 0.5
Body temperature (°C)	35.9 ± 0.3	37.5 ± 0.3**	35.5 ± 0.1	35.9 ± 0.3	35.8 ± 0.2	37.2 ± 0.07*	35.4 ± 0.1	35.7 ± 0.1
Food intake (g/day)	3.9 ± 0.0	0.78 ± 0.03***	3.5 ± 0.18	3.2 ± 0.2	3.7 ± 0.15	0.9 ± 0.1***	4.6 ± 0.15	4.15 ± 0.15
Leptin (ng/mL)	ND	73.8 ± 30.2††	ND	1.1 ± 0.5	ND	143 ± 16.4††	ND	1.1 ± 0.6

^* P < 0.05, ^** P < 0.01, ^*** P < 0.001 for differences between baseline and leptin pump; ^†† P < 0.01 for the difference between saline and leptin infusion. ND, not done. Results are presented as mean ± SEM.