Table 1.
Characteristics | EPCs (n = 5), n (%) | BMSCs (n = 5), n (%) | Placebo (n = 6), n (%) | p value |
---|---|---|---|---|
Age, years | 50.80 ± 14.11 | 49.40 ± 10.85 | 52.83 ± 14.95 | .915 |
Male | 4 (80.0) | 4 (80.0) | 5 (83.3) | .986 |
Married | 5 (100.0) | 5 (100.0) | 6 (100.0) | |
Body mass index, kg/m2 | 25.57 ± 3.83 | 23.08 ± 3.66 | 22.33 ± 1.73 | .278 |
Allergic | 1 (20.0) | 0 (0.0) | 0 (0.0) | .309 |
Time of cells culture | 40.80 ± 11.43 | 27.00 ± 7.17 | .342 | |
Risk factors | ||||
Smoking | 2 (40.0) | 2 (40.0) | 2 (33.3) | .965 |
Alcohol use | 1 (20.0) | 1 (20.0) | 0 (0.0)) | .504 |
Hypertension | 3 (60.0) | 4 (80.0) | 1 (16.7) | .09 |
Dyslipidemia | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Diabetes | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Coronary artery disease | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Atrial fibrillation | 2 (40.0) | 1 (0.0) | 1 (0.0) | .641 |
COPD | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
TIA | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Stroke mechanisms | ||||
Atherosclerotic | 3 (60.0) | 4 (80.0) | 5 (83.3) | .641 |
Cardioembolic | 2 (40.0) | 1 (20.0) | 1 (16.7) | .641 |
Cryptogenic | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Treatment | ||||
Thrombolytics | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Drugs | AP(3); AC(2) | AP(3); AC(2) | AP(4); AC(2) | |
mRS on 7th day | 3.40 ± 0.89 | 4.00 ± 1.22 | 3.67 ± 0.82 | .636 |
NIHSS on 7th day | 12.20 ± 4.92 | 17.60 ± 5.59 | 15.50 ± 3.02 | .632 |
Barthel index on 7th day | 39.00 ± 24.60 | 27.00 ± 30.74 | 25.00 ± 20.00 | .203 |
SSS on 7th day | 28.00 ± 17.38 | 18.20 ± 13.50 | 19.33 ± 10.39 | .483 |
Abbreviations: AC, anticoagulant; AP, antiplatelet agent; BMSCs, bone marrow stromal cells; bpm, beats per minute; COPD, chronic obstructive pulmonary disease; DBP, diastolic blood pressure; EPCs, endothelial progenitor cells; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood; SSS, Scandinavia Stroke Scale; TIA, transient ischemic attack.