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Hot-melt extrusion formulations for solid dispersions
| Formulation Name | Screw Speed (RPM) | Drug Content (%) | Acidifier Content (%) | Polymer Content (%) |
|---|---|---|---|---|
| N1 | 80 | 20 | 0 | 80 |
| N2 | 120 | 20 | 0 | 80 |
| N3 | 80 | 40 | 0 | 60 |
| N4 | 120 | 40 | 0 | 60 |
| N5 | 80 | 20 | 10 | 70 |
| N6 | 120 | 20 | 10 | 70 |
| N7 | 80 | 40 | 10 | 50 |
| N8 | 120 | 40 | 10 | 50 |
| N9 | 100 | 30 | 5 | 65 |
| N10 | 100 | 30 | 5 | 65 |
| N11 | 100 | 30 | 5 | 65 |
