Figure 3.

The orientation of microtubules changes with the sarcomere length, and correlates with mitochondrial deformation. (A) The minimum intersection angle between microtubules and the associated sarcomere plane decreases with increasing sarcomere length, n = 14 to 26 microtubules per group, N = 6 animals, analysis with one‐way ANOVA. (B) Representative 3D segmented models of microtubules in cells fixed in different deformation states; gray line illustrates axial orientation of associated sarcomeres. (C) Schematic of the correlation of microtubular orientation and mitochondrial deformation in different mechanical states.