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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: DNA Repair (Amst). 2018 Nov 13;73:64–70. doi: 10.1016/j.dnarep.2018.11.003

Fig. 4.

Fig. 4.

Cytotoxicity of PARP inhibitors toward wt and p12KO cells. (A-D) Cytotoxicity of the PARP inhibitors Olaparib, Niraparib, Rucaparib and Talazoparib respectively, as determined by clonogenic survival assays (Materials and Methods). Data are shown as survival fraction (mean ± SD, n=3) and plotted against the log of the drug concentrations. Symbols and lines for A549 cells, solid blue circles, solid blue line; A549-p12KO cells, solid blue circles, dotted blue line; H1299 cells, solid red squares, solid red line; H1299-p12KO, solid red squares, dotted red line.