Table 2.
T2DM-related indexes between baseline and 4 years of follow-up divided by the median of baseline circulating miRNAs
| miR-150 levels | miR-30a-5p levels | miR-15a levels | miR-375 levels | ||||||
|---|---|---|---|---|---|---|---|---|---|
| low | high | low | high | Low | high | low | high | ||
| DI | 0 y | 0.95 ± 0.03 | 0.93 ± 0.03 | 0.95 ± 0.03 | 0.92 ± 0.03 | 0.91 ± 0.04 | 0.96 ± 0.03 | 0.94 ± 0.03 | 0.93 ± 0.03 |
| 4 y | 0.94 ± 0.04 | 0.85 ± 0.03* | 0.94 ± 0.03 | 0.85 ± 0.04* | 0.89 ± 0.04 | 0.89 ± 0.04 | 0.87 ± 0.04 | 0.92 ± 0.04 | |
| HIRI | 0 y | 1069 ± 42 | 1040 ± 41 | 1020 ± 41 | 1088 ± 41 | 1046 ± 41 | 1062 ± 41 | 1027 ± 41 | 1080 ± 41 |
| 4 y | 958 ± 64 | 967 ± 61 | 947 ± 62 | 978 ± 62 | 986 ± 62 | 940 ± 62 | 1012 ± 62 | 914 ± 62* | |
| MISI | 0 y | 1.81 ± 0.14 | 2.19 ± 0.14 | 2.15 ± 0.14 | 1.86 ± 0.15 | 2.31 ± 0.14 | 1.73 ± 0.14 | 1.99 ± 0.14 | 2.03 ± 0.14 |
| (x102) | 4 y | 2.02 ± 0.15 | 1.79 ± 0.14* | 1.82 ± 0.15 | 1.98 ± 0.15 | 2.17 ± 0.15 | 1.65 ± 0.14 | 1.97 ± 0.15 | 1.83 ± 0.15 |
| ISI | 0 y | 3.84 ± 0.18 | 4.10 ± 0.17 | 3.99 ± 0.17 | 3.97 ± 0.17 | 4.13 ± 0.17 | 3.84 ± 0.17 | 3.96 ± 0.17 | 4.01 ± 0.17 |
| 4 y | 3.98 ± 0.19 | 3.71 ± 0.18* | 3.83 ± 0.18 | 3.84 ± 0.18 | 4.20 ± 0.18 | 3.50 ± 0.18 | 3.86 ± 0.18 | 3.81 ± 0.18 | |
Values are expressed as the mean ± SEM and were obtained by ANOVA for repeated measures. Low: Low circulating levels of miRNAs; High: High circulating levels of miRNAs. Statistical significance was evaluated by the Wilcoxon test using SPSS (now PASW Statistics for Windows (version 21.0) (IBM. Chicago, Illinois))
*Statistically significant differences (p < 0.05) are in bold