Table 2.
Association between haplotypes of PSORS1C1 and STARD3 and NM23 expression.
| Haplotypes | NM23 | Ad OR★ | P–value | Ad HROS † | P–value | Ad HRRFS † | P–value | |||
|---|---|---|---|---|---|---|---|---|---|---|
| — | 1+ | 2+ | 3+ | (95% CI) | (95% CI) | (95% CI) | ||||
| PSORS1C1 | ||||||||||
| TGCACA | 40 | 273 | 61 | 63 | Ref. | Ref. | Ref. | |||
| CAGGTG | 37 | 171 | 19 | 20 | 0.44 (0.3 0–0.65) |
2.70 × 10 -5 | 0.71 (0.42–1.22) |
0.219 | 0.87 (0.46–1.63) |
0.653 |
| CAGACA | 6 | 64 | 9 | 5 | 0.56 (0.32–0.99) |
0.048 | 0.99 (0.65–1.51) |
0.967 | 1.66 (0.95–2.90) |
0.073 |
| Othersa | 3 | 36 | 3 | 6 | 0.60 (0.3 0–1.18) |
0.135 | 0.97 (0.74–1.27) |
0.805 | 2.04 (0.99–4.20) |
0.054 |
| All othersb | 46 | 271 | 31 | 31 | 0.48 (0.35–0.68) |
2.05 × 10 -5 | 0.93 (0.73–1.18) |
0.561 | 0.74 (0.50–1.10) |
0.136 |
| STARD3 | ||||||||||
| GG | 46 | 329 | 58 | 69 | Ref. | Ref. | ||||
| Othersc | 40 | 209 | 34 | 25 | 0.65 (0.47–0.91) |
0.012 | 0.97 (0.76–1.24) |
0.814 | 1.18 (0.74–1.88) |
0.498 |
Note. ★OR, †HR and P–value are adjusted for age, gender, race, smoking status, drinking status, BMI, BCLC stage, Child–Pugh stage, preoperative serum AFP level, TACE status before hepatectomy, pathological grade, cirrhosis, intrahepatic metastasis, PVTT, regional invasion, radical resection, and use of antiviral therapies. aOthers include CGCACA and CGGGCA. bThe group of all others is merged CAGGTG, CAGACA, CGCACA, and CGGGCA. cOthers include CA, GA, CG, and the total number of patients harbour GA and CG is 6.
Abbreviations. OR: odds ratio; HR: hazard ratio; 95% CI: 95% confidence intervals; Ad: adjusted.