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. 2018 Nov 30;3(1):63–73. doi: 10.1002/hep4.1286

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© 2018 The Authors. Hepatology Communications published by Wiley Periodicals, Inc., on behalf of the American Association for the Study of Liver Diseases.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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MR spectroscopic results. Creatine ratios of the three metabolites in patients with cirrhosis (red bars) and patients without cirrhosis (blue bars) are shown as mean ± SDs. P values of comparisons are displayed, with * indicating significant difference. (A) Glutamate + glutamine, (B) myo‐inositol, and (C) choline. There was a significantly higher glutamate + glutamine and lower myo‐inositol and choline in patients with cirrhosis compared to patients without cirrhosis (controls) at all sites except PGM glutamate + glutamine. Abbreviations: ACC, anterior cingulate cortex; Cirr, cirrhosis; NoCirr, without cirrhosis; PGM, posterior gray matter; RPWM, right parietal white matter.