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G5 HEV infection in cynomolgus monkeys. Two naive monkeys, M4769 and M4770, and two monkeys positive for anti‐HEV IgG, M4693 and M4694, were intravenously inoculated with G5 HEV, and the kinetics of the RNA, antibodies, and ALT were measured. The G5 HEV RNA copy numbers in the feces (○) and sera (△) were determined by RT‐qPCR. Anti‐HEV IgG (△) and anti‐HEV‐IgM (□) in sera were determined by ELISAs. ALT (◊) in monkey sera were determined by a commercial kit.
