. Author manuscript; available in PMC: 2019 Feb 1.

Published in final edited form as: Addict Biol. 2017 Nov 27;24(1):132–144. doi: 10.1111/adb.12578

Table 5.

Univariate SNP-heritability [h²_SNP (SE)] of AD factor for EAs and AAs.

	h²_SNP Gene set A	h²_SNP Gene set B	Total SNP-Heritability
European Ancestry	0.17 (0.05)^***	0.10 (0.04)^**	0.27 (0.05)^a
African Ancestry	0.24 (0.15)^*	0.07 (0.14)	0.30 (0.15)^a

Note: Table presenting the univariate SNP-heritability of AD factors for EAs and AAs using subsets of SNPs (Gene set A comprises SNPs that survive within-ancestral-group quality control procedures [QC] across both populations; Gene set B includes SNPs that differentially survive QC across ancestral groups; Total SNP-heritability reflects the genomewide effects of Gene sets A & B within each ancestral group). Notations:

p < 0.05,

^**

p < 0.01,

^***

p < 0.001;

significance test not available for total heritability in model, as the likelihood ratio test is conducted only on the specific variance components within the model.