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. 2018 Nov 26;10(1):103–110. doi: 10.1111/1759-7714.12917

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© 2018 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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PD‐L1 tumor proportion score (TPS) in several cases of adenocarcinoma with positive fluorescence in situ hybridization (FISH) ROS1 split signal. (a) Case no. 407 showed adenocarcinoma histology (left panel), positive ROS1 FISH, mainly break‐apart signal (middle panel), and high PD‐L1 expression (right panel). (b) Case no. 404 showed adenocarcinoma histology (left panel), positive ROS1 FISH, mainly isolated green signal (middle panel) and high PD‐L1 expression (right panel). (c) Case no. 282 showed adenocarcinoma histology (left panel), positive ROS1 FISH, mainly break‐apart signal (middle panel), and low PD‐L1 expression (right panel). (d) Case no. 396 showed adenocarcinoma histology (left panel), positive ROS1 FISH, mainly isolated green signal (middle panel), and low PD‐L1 expression (right panel).