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. 2018 Dec 14;50(4):328–339. doi: 10.3947/ic.2018.50.4.328

Table 3. In vitro activities of the antimicrobial agents tested against the 135 Streptococcus pneumoniae isolates.

Antibiotic MIC50 MIC90 Range S (%) I (%) R (%)
Penicillin 0.032 0.75 <0.016–4 65.2 27.4 7.4
Amoxicillin 0.032 2 0.016–64 90.4 5.9 3.7
Cefuroxime 0.047 2 0.016–12 80 6.7 13.3
Cefotaxime 0.047 0.75 <0.016–8 95.6 2.2 2.2
Cefepime 0.19 1 0.016–8 91.2 4.4 4.4
Imipenem 0.047 0.125 0.002–3 91.9 5.9 2.2
Meropenem 0.047 0.25 0.002–3 92.6 5.9 1.5
Erythromycin 0.064 ≥256 0.016–≥256 69.6 - 30.4
Clindamycin 0.064 ≥256 0.016–≥256 84.4 - 15.6
Ciprofloxacin 0.75 1 0.023–≥32 97.8 - 2.2
Levofloxacin 0.75 1 0.032–≥32 98.5 - 1.5
Moxifloxacin 0.125 0.19 0.016–≥32 98.5 - 1.5
Chloramphenicol 2 3 0.19–12 98.5 - 1.5
Tetracycline 0.25 32 0.047–≥256 83.7 - 16.3
TMP/SMX 0.094 2 0.012–≥32 83.7 8.9 7.4
Vancomycin 0.38 0.5 0.016–1 100 - 0.0
Linezolid 0.75 1 0.023–2 100 - 0.0
Quinupristin/dalfopristin 0.38 1 0.125–4 91.1 5.9 3
Tigecycline 0.047 0.25 0.016–1.5 99.3 - 0.7
Daptomycin 0.094 0.125 0.016–0.75 100 - 0.0

S, susceptible; I, intermediate; R, resistant; TMP/SMX, trimethoprim-sulfamethoxazole.